Developing the 2013 WHO consolidated antiretroviral guidelines.
نویسندگان
چکیده
The 2013 ‘Consolidated guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection’ [1], released in July 2013, are the latest and most comprehensive of a series of important guidelines on antiretroviral therapy (ART) over the last decade from the World Health Organization (WHO). They were developed in response to important advances in the science and practice of HIV care since publication of the 2010 WHO guidance for adults and adolescents [2], pregnant women [3] and children [4]. This includes evolving evidence on the preventive and individual clinical benefits of earlier ART, innovations in service delivery such as the progressive decentralization of HIV testing and care, and the more widespread availability and affordability of once-daily fixed-dose combinations (FDCs) ART regimens [5].
منابع مشابه
Commentary: Operational Guidance in the 2013 WHO consolidated antiretroviral guidelines.
The new guidelines promote initiating ARVs with a CD4þ T-cell threshold of 500 cells/ml or less for adults, adolescents, and older children [1]. These guidelines further recommend ARVs, regardless of CD4þ T-cell count, for patients with active tuberculosis (TB), pregnant and breastfeeding women, and children younger than 5 years of age [1]. This is a call for action to countries to further scal...
متن کاملAdoption of national recommendations related to use of antiretroviral therapy before and shortly following the launch of the 2013 WHO consolidated guidelines.
OBJECTIVE To determine the status of key national policies on the use of antiretroviral therapy (ART) at the time of the launch of the 2013 WHO consolidated guidelines as well as to track early progress towards adoption of these recommendations following dissemination. DESIGN Descriptive analysis of global data on baseline ART policies as of June 2013 and early intentions to adopt the 2013 WH...
متن کاملThe role of mathematical modelling in the development of recommendations in the 2013 WHO consolidated antiretroviral therapy guidelines.
Despite the exponential growth in the literature on modelling and simulation studies of impact and cost-effectiveness in different aspects of healthcare, there is no clear consensus on the appropriate role of modelling in the development of recommendations in clinical guidelines. This is compounded both by the lack of a standardised approach to assess the quality of modelling, and lack of clari...
متن کاملCommentary: When to start and what to use in children--recommendations and rationale.
The 2013 WHO consolidated guidelines recommend treating all HIV-infected children under the age of 5 years regardless of CD4þ T-cell count or WHO clinical stage, and treating children aged 5 years and older according to the same criteria as for adults: WHO clinical stage 3 or 4 or CD4þ T-cell count of 500 cells/ml or less [1]. Guideline recommendations for what drugs to use for initial antiretr...
متن کاملImproving antiretroviral therapy scale-up and effectiveness through service integration and decentralization.
BACKGROUND Current service delivery systems do not reach all people in need of antiretroviral therapy (ART). In order to inform the operational and service delivery section of the WHO 2013 consolidated antiretroviral guidelines, our objective was to summarize systematic reviews on integrating ART delivery into maternal, newborn, and child health (MNCH) care settings in countries with generalize...
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ورودعنوان ژورنال:
- AIDS
دوره 28 Suppl 2 شماره
صفحات -
تاریخ انتشار 2014